First Script saw continued decreasing opioid trends across our retail and mail-order programs in 2019, even while overall prescription trends saw a slight upward shift in utilization per claim and cost per claim. Even with these changes, opioids remain the #1 therapeutic class by usage and cost, however, 2019 marked the largest reduction of the last 5 years in the percentage of opioid scripts with greater than or equal to 90 MED. View the video blog here.