Part 2: Total View of Prescription Cost and Utilization Trends Across In-Network and Out-Of-Network Channels 

This analysis examines the trends observed within our combined prospectively and retrospectively managed network channels to provide a comprehensive view of prescription activity. While overall trends continue to align with evidence-based recommendations in key areas of interest, the cost of prescriptions is increasing. This rise is primarily driven by three factors: high-cost topical agents that are almost exclusively obtained from out-of-network channels, increased utilization and spending within the migraine category, and rising trends in the average wholesale price for certain drug products, particularly brand medications.